Drug release is the process by which an active ingredient is released from its formulation for absorption and therapeutic action. This process is critical for the drug’s efficacy and can be designed to release the drug in an immediate, controlled, sustained, or targeted manner. Drug delivery systems, such as polymeric matrices, liposomes, or microspheres, enable prolonged or localized release, optimizing bioavailability and minimizing side effects. The choice of the appropriate release system is based on the drug’s properties and the need to maintain effective therapeutic levels while reducing systemic toxicity.