Diseases of the circulatory system are conditions that affect the heart or blood vessels. These diseases are the leading cause of death worldwide, responsible for 17.5 million deaths annually. Among the main circulatory system diseases are atherosclerosis, stroke, cardiac fibrosis, myocardial infarction, and arrhythmias, among others.
To investigate these diseases, cellular and animal models are used to study the underlying mechanisms and test new therapies. These models are essential for understanding how these diseases develop and progress, as well as for identifying potential treatments that can improve quality of life and reduce associated mortality. Research using these models has advanced significantly in recent decades, providing valuable insights that have contributed to the development of innovative drugs and medical techniques.