Our goal is the development of advanced therapies based in cell therapy and tissue engineering. We ...developing and evaluating novel biomaterials to be used as scaffolds inTE or as drug deliverers. We also work with adult and perinatal stem cells to be used as drugs per sé or as part of TE products.
Leonor Santos Ruiz
Research lines
Advanced prostheses and implants based on 3D printing
Use of 3D printing technology to design novel customised prosthetic implants.
Implementation through bioactive coatings and tissue engineering elements (molecules, cells or cell products, resorbable biomaterials)
Research on the therapeutic potential of different stem cell types (adult and perinatal SC). Determination of the culture conditions needed to use SC as therapeutic product per sé, or as part of a tissue engineering product.
Research on the therapeutic potential of stem cell products (exosomes, secretome...).
Development and evaluation of biomaterials to be used as tissue substitutes (mainly bone) in reconstructive surgery, or as a scaffold in tissue engineering.
Our goal is developing products for humans, but since preclinical evaluation takes place in animals (rat, rabbit, minipig), we have sometimes collaborated with veterinarians, finding novel applications to our research.
Research projects
Canine adipose tissue mesenchymal stem cell secretome (CAD-MSCS) and development of its clinical application in veterinary medicine (SecMeV)
Year: 2019 Call: Consejería de Economía y Conocimiento - Junta de Andalucía (Programa Operativo FEDER de Andalucía 2014-2020)
Proof of concept to reach TRL 4 for an immunomodulatory product based on human umbilical cord mesenchymal stem cell exosomes, for use in severe cases of Covid-19. Development of in vitro and in vivo tests (EXOMOD)
Year: 2020 Call: I Plan Propio de Investigación y Transferencia de la Universidad de Málaga
Preclinical evaluation of personalized, bioprinted, implants for the surgical correction of critical-sized cranio-maxillofacial defects in pediatric patients (FacePrint)
Year: 2023 Call: AES 2022. Instituto de Salud Carlos III
Biomechanical and biological analysis of the combination of osteosynthesis system and scaffold for the repair of segmental bone defects (SEGBONREP)
Year: 2021 Call: Ministerio de Ciencia e Innovación, Proyectos I+D+i 2020 Retos Investigación
Research lines
Research projects
en
ES